PLAU and gastric cancer: TGF-beta signaling pathway has also been found to be enriched in gastric cancer (Huang et al., 2020), and it is involved with the telomerase (hTERT) enzyme in upregulating the urokinase-type plasminogen activator (uPA) for endothelial-mesenchymal transition (EMT) (Jaiswal and Yadava, 2020; Jaiswal and Yadava, 2019).