Earlier studies have reported that beta sitosterol downregulates beta catenin expression inhibits growth and induces apoptosis in colon cancer cells.66 We presume that the active phytoconstituents ofKadukkai maathirai could modulate the intracellular transcription process by inhibiting the armadillo repeat region of β catenin. This evidence concerns the gene CTNNB1 and malignant colon neoplasm.