TP53 and cancer: Additionally, we identified correlations between these common genera and pathways in Genetic Information Processing (DNA replication, nucleotide excision repair), Environmental Information Processing (PI3K-Akt, Notch, and Hippo signaling pathways), Cellular Processes (p53 signaling pathway), Organismal Systems (T and B cell receptor signaling pathways, IL−17 signaling pathway), and Human Diseases (Platinum drug resistance, Pathways in cancer, Small cell lung cancer) (Supplementary Figures 1–5).