HNF1B and melanoma: Consistently, the protein level of HNF1B is also highest in 786-O ccRCC cell line compared to other cancer cell lines, such as SW620 (colorectal cancer), HeLa (cervical carcinoma), KTC-1 (thyroid cancer), T24 (bladder cancer), A375 (melanoma), H1299 and A549 (non-small cell lung cancer) (Fig. 1C).