Upon reanalyzing hepatocyte gene expression critical for liver steatosis and hepatic lipogenesis using RT-qPCR (n = 11), we confirmed the NGS RNA Seq data showing that stearoyl-CoA desaturase (Scd1), which encodes the rate-limiting enzyme in the formation of monounsaturated fatty acids, is significantly downregulated (P = 0.0036) following treatment with MI-883. Here, SCD is linked to fatty liver disease.