Microbiota profiles have been linked to clinical-pathological characteristics of HCC patients, such as AFP, ALT, and AST levels, and have shown predictive value for HBV-related HCC microvascular invasion.559,560 Additionally, the presence of specific gut microbes, such as B. longum, has been associated with improved liver function recovery in HCC patients during the perioperative period.561. Here, GPT is linked to hepatocellular carcinoma.