NFKB1 and allergic rhinitis: 1,5-isoquinolinediol, a poly (ADP-ribose) polymerase (PARP) inhibitor, has been shown to significantly inhibited inflammatory cell infiltration and the NF-κB signaling pathway [68, 69], The NF-κB signaling pathway is involved in activating dendritic cells (DCs) and is an inevitable pathway for the development of allergic rhinitis [70].