We analysed iPSC obtained from (i) a PD patient carrying the RHOT1 c.815G>A mutation (NM_001033568; p.R272Q Miro1, PD-R272Q); (ii) the corresponding gene-edited line where the point mutation was corrected by CRISPR/Cas9 (isogenic control, iCtrl)18; and (iii) control lines from age- and sex-matched healthy individuals (Ctrl) (Fig. 1A and Table 1). The gene discussed is RHOT1; the disease is Parkinson disease.