A prior study demonstrated that HIF1A promotes lung cancer progression by enhancing invasion and vasculogenic mimicry (VM).[15] Additionally, HIF1A has been implicated in the modulation of ferroptosis in liver cancer, further emphasizing its importance in cancer biology.[16] Therefore, we speculate that YFJDT may exert its therapeutic effects in lung cancer by modulating HIF1A‐mediated pathways, thus promoting ferroptosis and suppressing EMT and VM. The gene discussed is HIF1A; the disease is lung cancer.