A prior study demonstrated that HIF1A promotes lung cancer progression by enhancing invasion and vasculogenic mimicry (VM).[15] Additionally, HIF1A has been implicated in the modulation of ferroptosis in liver cancer, further emphasizing its importance in cancer biology.[16] Therefore, we speculate that YFJDT may exert its therapeutic effects in lung cancer by modulating HIF1A‐mediated pathways, thus promoting ferroptosis and suppressing EMT and VM. This evidence concerns the gene HIF1A and cancer.