Multivariable model further adjusted for age, gender, FBG, hs‐CRP, BMI, WC, hypertension, physical activity, smoking status, drinking status, family cancer history, and other lipid biomarkers slightly weakened but did not materially alter this positive trend (adjusted HRQ2vs.Q1 = 1.08, 95% CI: 0.64–1.84; adjusted HRQ3vs.Q1 = 1.83, 95% CI: 1.14–2.96; adjusted HRQ4vs.Q1 = 2.50, 95% CI: 1.57–3.98; ptrend < 0.0001). The gene discussed is CRP; the disease is Hypertension.