By analyzing the Gene Expression Profiling Interactive Analysis (GEPIA) database (http://gepia.cancer‐pku.cn/)[43] and GSE53625 dataset[44] from the NCBI's Gene Expression Omnibus (GEO) database, we found that MNX1 mRNA was upregulated in ESCA as well as its subtype ESCC (Figure6a,b). The gene discussed is MNX1; the disease is esophageal squamous cell carcinoma.