INS and type 1 diabetes mellitus: Patients living with T1DM experience various challenges, related mainly to a restrictive lifestyle, multiple daily insulin injections, and monitoring of blood glucose levels.6 The process to manage this chronic disease impacts the HRQoL of the children/adolescents, and interferes also with the familial dynamics and the parents’ HRQoL.32 This study provides results useful for assessing HRQoL in patients with chronic diseases living in Tunisia, and North Africa.