For females, compared to the non-NAFLD group, the NAFLD group showed significantly increased BMI, VFA, SFA, SBP, DBP, TC, LDL-c, TG, TG/HDL-c ratio, FPG, ALT, AST, GGT, UA, Hb, FINS and HOMA-IR (all P < 0.05), while age, diabetes duration, HDL-c, Scr, UACR and SPISE were significantly decreased (all P < 0.05). Here, GSTM1 is linked to metabolic dysfunction-associated steatotic liver disease.