Finally, based on the variables that entered the model last, the formula used to calculate SPISE and the insulin resistance-related indicators, the predictive capabilities of SPISE, HDL-c, diabetes duration, Scr, VFA, BMI, GGT, ALT, TG, TG/HDL-c ratio, HOMA-IR, Hb, UA, and TC for NAFLD were evaluated separately for different genders (Table 6). Here, GSTM1 is linked to metabolic dysfunction-associated steatotic liver disease.