However, statistically significant variances (P < 0.05) were noted between the new fracture group and the non-fracture group in terms of age, diabetes, hemoglobin (HB), total protein (TP), serum albumin (ALB), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), β-CTX, PTH, 25-OH-D3, number of fractured vertebrae, BMD, exercise regularly after discharge, anti-osteoporosis after discharge. The gene discussed is ALB; the disease is diabetes mellitus.