The KEGG enrichment analysis showed that the ARDEGs in epilepsy were not only implicated in the autophagy, but also the pathways in cancer, apoptosis, NOD-like receptor signaling pathway, AGE-RAGE signaling pathway in diabetic complications, C-type lectin receptor signaling pathway, neurotrophin signaling pathway, etc. Recently, research has been conducted to explore the role of autophagy in epilepsy. This evidence concerns the gene BDNF and epilepsy.