From multivariate logistic regression analysis, we identified four independent LNM-positive predictors: tumor size (OR = 2.613; 95% CI: 1.130–6.468; P value = 0.029), CTR (OR = 3.428; 95% CI: 1.196–12.540; P value = 0.035), pleural indentation (OR = 4.441; 95% CI: 1.899–11.499; P value = 0.001), and CEA values (OR = 6.521; 95% CI: 2.537–17.196; P value < 0.001) (Table 4). The gene discussed is CEACAM5; the disease is neoplasm.