Interestingly, we found that the most significant canonical pathway is IL17A in Psoriasis [pvalue: 2.65E-08, -log (p-value: 7.58)] amongst 16 canonical pathways identified by IPA with a p-value of ≤ 0.05 (Figure 2B; Supplementary Table S4). The gene discussed is IL17A; the disease is psoriasis.