Of note, potentially pathogenic variants in genes previously associated with psoriasis such as PSORS1-13, MHC, I, TNF, and TRAF3IP2 (23–26), and genes implicated in CMC, including STAT1, AIRE, IL17F, IL17RC, and RORC (27–29) were absent in our patient. The gene discussed is TNF; the disease is psoriasis.