High expression of SAA is significantly related to extranodal lesions, elevated LDH (Lactate Dehydrogenase) levels, and high NCCN-IPI (National Comprehensive Cancer Network-International Prognostic Index) scores, with shorter survival times compared to the control group (34) in human diffuse large B-cell lymphoma (DLBCL), indicating a poor prognosis (Figure 2B). Here, SAA1 is linked to diffuse large B-cell lymphoma.