GFAP and encephalitis: Patients with A-GFAP-A most commonly present with non-specific subacute meningitis symptoms (fever, headache, neck stiffness, vomiting), encephalitis (altered consciousness, tremors, mental symptoms, seizures), myelitis (sensory and motor disorders), cerebellar ataxia, and blurred vision (optic disc edema), with meningeal encephalomyelitis and meningoencephalitis being their main clinical phenotypes (1, 9, 40).