This document outlines the planned analyses for the primary publication of the results of the LAST ACT clinical trial (‘a Leukotriene A4 hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-negative adults with Tuberculous meningitis’ [clinicaltrials.gov, NCT03100786, posted 04-04-2017, URL:https://clinicaltrials.gov/study/NCT03100786]). Here, LTA4H is linked to meningeal tuberculosis.