Presently, chronic kidney disease (CKD) is delineated by markers of kidney impairment, involving imaging or proteinuria (typically assessed through the albumin-to-creatinine ratio: ACR) and diminished renal function (falling below the glomerular filtration rate: GFR thresholds, estimated from the serum creatinine concentration) (1–3). This evidence concerns the gene ALB and chronic kidney disease.