The proteins that were altered by obesity in both models were GC, RPLP0, EMILIN1, HSPG2, CALU, RABEP2, TSC22D1, SLMAP, FH, SERPINA6, ENSA, NAP1L1, SAE1, HPRT1, ELOB, and DENR. This evidence concerns the gene DENR and Obesity.