IL6 and respiratory failure: In a small retrospective cohort study of 141 patients by Wu et al., IL-6 concentrations greater than 108 pg/mL and D-dimer concentrations greater than 14.0 μg/mL, including respiratory failure, liver failure, digestive system dysfunction, sepsis, and multiple organ dysfunction (listed in order of prevalence), predicted early poor postoperative prognosis [8].