IGF2BP3 and hepatocellular carcinoma: To explore the mechanism of NC against HCC, we treated Huh7 cells with 4 μmol/L of NC for 48 h and performed RNA-seq. A total of 8993 DEGs were obtained (Fig. 6A), with IGF2BP3 being a gene that showed significant downregulation in expression after NC treatment (log2FoldChange = -0.914, P < 0.01, Fig. 6B).