TF and hepatocellular carcinoma: Our previous studies have also demonstrated that NC can exert anti-HCC effects by mechanisms involving multiple networks of epigenetic regulation, such as cicRNA-miRNA-mRNA (Xiong et al. 2019), lncRNA-TF-mRNA (Gao et al. 2019b), and TF-miRNA-mRNA (Gao et al. 2019a).