CD8A and neoplasm: We observed that the number of CD8 located in the IT region was not impacted by the level of G9 expression on tumor cells (Fig. 1E), but those patients with CD8-low localization in the IT region and G9-high tumors had a significantly lower OSR at 5 years (63.64%; 7/11; turquoise line) compared to those with CD8-high localization in the IT region and G9-low tumors (100%; 9/9; p = 0.012; orange line; Fig. 1F).