Similarly, A10-PPARα-treated mice presented a significant reduction in tumor volume with pemafibrate compared with the A10-PPARα control group (DMSO: 312.69 ± 65.92 mm3 vs Pem: 131.94 ± 37.59 mm3, mean reduction of 57.8%), with the effect on tumor suppression being more pronounced than that in WT mice. The gene discussed is PPARA; the disease is neoplasm.