The expression levels of the six target genes were analyzed in endometrial cancer and normal endometrial tissues in the TCGA-UCEC and CPTAC cohorts (MFSD3 expression data were not available in the datasets); the results revealed that these selected target genes were overexpressed in endometrial cancer tissues (Fig. 5f, g and Supplementary Fig. 2d). The gene discussed is SLC33A2; the disease is endometrial cancer.