The paired analyses of T-bet co-expression in GATA-3+ cells derived from MLN and siLP of individual mice showed that the cells from both organs comprised similar proportions of Th2/1 hybrid cells in the untreated infection controls and, at a higher level, in mice treated with IFN-γ early during the infection, indicating that naturally as well as experimentally induced Th2/1 hybrid cells migrated to the infected small intestine with similar efficiency as classical Th2 cells (Fig. 4B). The gene discussed is IFNG; the disease is infection.