PRL and posterior cortical atrophy: Despite the absence of differences of PRL (in plasma) or PRLR (in tissue) between PCa patients and healthy subjects, it was recently reported that metastatic CRPC patients with low PRL plasma levels had a better response to abiraterone treatment when compared to patients with high PRL plasma levels, suggesting a predictive value of PRL plasma levels of the response to abiraterone treatment [96].