luminal A phenotype, positive to hormone receptors).[7, 8] The same opposite pattern of expression was found in colon cancer where NTS1 is overexpressed in 76 % of colon adenocarcinomas[9] and is associated with inflammatory bowel disease‐related oncogenesis[10] while it is undetectable in normal colonic epithelium. This evidence concerns the gene NTS and malignant colon neoplasm.