AFP and neoplasm: In Asia, where living donor liver transplantation (LDLT) predominates, the “5–5–500 rule” (tumors ≤ 5 cm in size, tumor number ≤ 5, and Alpha-fetoprotein: AFP level ≤ 500 ng/mL) has shown promising results in regional variations in organ availability have led to different transplantation approaches [66, 67].