CSF3R and chronic neutrophilic leukemia: In 19 consecutive patients with CNL, cases presenting with CSF3R T618I variant showed higher lymphocyte counts, lower hemoglobin value and platelet count, and worse clinical outcome compared to other CSF3R mutations i.e., M696T and T640N, suggesting that the type of CSF3R mutations could identify phenotypically and prognostically different subsets in CNL [50].