ILK and cancer: The mTOR-independent ILK/RICTOR complex was detected in several cancer cell lines and is involved in Transforming Growth Factor (TGF) beta-1-mediated EMT.48 RICTOR promotes tumor progression regulating the tumoral microenvironment by increasing cell proliferation and survival, decreasing apoptosis in cancer cells, facilitating angiogenesis, and remodeling the stroma.