This was consistent with that overexpression of CITED2 significantly suppressed cell growth in HepG2 and BEL7404 hepatocellular carcinoma cell lines, whether CITED2 knockdown significantly increased cell viability and clonogenicity, and promoted G1‐S phase transition in the hepatocyte cell line LO2 and HCC cell line Hep3B [28]. This evidence concerns the gene CITED2 and hepatocellular carcinoma.