Given the distinctive ACRG expression pattern observed in glioma patients, we integrated the transcriptome data from the TCGA-GBMLGG (containing 529 LGG and 166 GBM patients), CGGA-692 (containing 443 LGG and 249 GBM patients), and CGGA-321 (containing 182 LGG and 139 GBM patients) datasets and re-performed consensus clustering analysis. The gene discussed is COMMD6; the disease is glioma.