Some studies have found that IL-17E can induce c-RAF phosphorylation, ERK1/2 and p70 S6 kinase are involved in the proliferation and survival of tumor cells, aggravation of docetaxel resistance of breast cells, and induction of cyclin E (LMW-E) production, whose high level is closely related to the poor survival rate of breast cancer patients. The gene discussed is CCNE1; the disease is neoplasm.