Another similar study tested doses from 0 to 80 μM of curcumin on 697, REH, SupB15, and RS4; 11 cells and found out curcumin treatment induces a dephosphorylation of the constitutive phosphorylated AKT/PKB which leads to suppressing cancer cell growth and apoptosis induction (Kuttikrishnan et al., 2019). The gene discussed is AKT1; the disease is cancer.