Studies have shown that specific TCM components, such as Tanshinone IIA (40) and Sanggenon C (41), inhibit the expression of c-Myc, along with signaling and transcription activators like STAT3 and HIF-1α in gastric cancer tissues, indirectly reducing AEG activity and thus curtailing tumor proliferation and metastasis. This evidence concerns the gene STAT3 and gastric cancer.