COL3A1 and Ehlers-Danlos syndrome, vascular type: To establish the diagnosis of vEDS, genetic testing was performed using DNA extracted from the patient’s peripheral blood. The analysis, outsourced to a certified genetic laboratory, involved whole-exome sequencing (WES) followed by targeted Sanger sequencing to confirm the results. This identified a heterozygous pathogenic mutation in the COL3A1 gene, a hallmark of vEDS.