IL6 and eye infection: Latent ocular infection was also associated with increased levels of inflammatory and angiogenic factors (including IL-6 and VEGF)90,91 as well as retinal and choroidal pathologies (including deposits at basal and apical aspects of the RPE, photoreceptor degeneration, and CNV).90, 91, 92 To note, the number of macrophages observed in CNV lesions were similar in infected and uninfected VEGF-Ahyper mice and did not represent the majority of VEGF-positive cells.90