ERBB2 and cancer: Bimetallic MOF-based aptasensors were successfully developed forthe detection of cancer cells.67−69 For example, the carbohydrateantigen 125 aptamer was anchored on the MOFs consisting of Tb andFe metal sites and used to detect MCF-17 cells.67 Aptamer strands were immobilized on carbon dot-doped Zr&Hf-MOF,and the resulting aptasensor was used as an ultrasensitive platformfor the early diagnosis of HER2- and HER2-overexpressing living cancercells.74