Therefore, adropin preserves immune system homeostasis and exerts anti-inflammatory effects in a variety of conditions, including atherosclerosis (9), diabetes (14–16), non-alcoholic fatty liver disease (NAFLD) (6, 17), non-alcoholic steatohepatitis (NASH) (10), and inflammatory bowel disease (18). The gene discussed is ENHO; the disease is metabolic dysfunction-associated steatotic liver disease.