Patients without IUAs generally had a longer duration of infertility (3.59 ± 2.35 years vs. 2.91 ± 1.88 years, P<0.001) and higher basal luteinizing hormone (LH) levels (5.34 ± 10.96 vs. 5.05 ± 6.02, P=0.014) than those with IUAs did; other basic characteristics, such as female age, BMI, number of oocyte retrieval cycles, AFC, FSH level, and anti-Müllerian hormone (AMH) level, were not significantly different between the two groups (P>0.05). The gene discussed is PLOD1; the disease is Infertility.