Studies have revealed that MAGE-A4 is expressed in approximately 50% of cases of nasopharyngeal carcinoma, oral squamous cell carcinoma, and laryngeal cancer, with expression rates reaching up to 90% in certain cancer types (Figueiredo et al. 2006; Brisam et al. 2016). Here, MAGEA4 is linked to oral cavity squamous cell carcinoma.