MAGEA4 and neoplasm: MAGEA4 protein expression is related to immune cell infiltration, with high MAGEA4 expression associated with M2-type macrophages (CD163) and regulatory T cells (FOXP3), while low MAGEA4 expression is associated with T cells (CD3), suggesting MAGEA4 may have immunogenic effects in the local tumor microenvironment (Hikmet et al. 2023).