Various studies have reported cases in which nonsense, or small insertion/deletion mutations of the TAB2 gene result in congenital heart disease and dilated cardiomyopathy (Chen et al. 2020; Engwerda et al. 2021; Koene et al. 2022; Vasilescu et al. 2018). The gene discussed is TAB2; the disease is dilated cardiomyopathy.