Additionally, the albumin-HMCD adducts can be actively taken up by cancer cells through various receptors that import albumin (gp60, gp18, and gp30 cell surface glycoproteins, megalin/cubilin complex, secreted protein acidic and rich in cysteine (SPARC), and FcRn), often overexpressed in cancer cells [19]. Here, CUBN is linked to cancer.