The small nucleolar RNA host gene 17 (SNHG17), a lncRNA involved in cell progression and migration in several cancers, is upregulated by YY1 in GBM allowing the activation of the Wnt pathway by sponging miR-506-3p a direct negative regulator of catenin beta 1, extending its half-life and consequently facilitating glioma progression [221]. The gene discussed is YY1; the disease is central nervous system cancer.