Herein, we demonstrate that anti-human PSMA or EGFR Abs increase in vitro phagocytosis of Myc-CaP (MC) prostate cancer cells expressing human PSMA or EGFR (hPSMA, hEGFR) by macrophages derived from murine p50-IMC. This evidence concerns the gene NFKB1 and Familial prostate cancer.