p50-IMC develop into macrophages and dendritic cells, and although mature myeloid progeny of p50-IMC comprise only ~ 2% of tumor myeloid cells after a single injection, after three p50-IMC injections tumor CD8+ T cell numbers increase fourfold and the proportion of CD8+ T cells that express IFNγ increases twofold. Here, IFNG is linked to neoplasm.