NFKB1 and prostate carcinoma: In the immune-competent B6CaP murine prostate cancer model, adoptive transfer of syngeneic immature myeloid cells lacking NF-κB p50 (p50-IMC), administered after a single dose of 5-fluorouracil (5-FU), slows tumor growth > threefold, whereas 5-FU followed by immature myeloid cells from wild-type mice, 5-FU alone, or p50-IMC alone are ineffective [8].