CFTR and infection: Flow-cytometry based cellular analysis, according to the gating strategy in S1 Fig, of BAL fluid after 6 and 18 hours post infection demonstrated that although alveolar macrophage numbers decreased in both groups post-infection, there was a significantly greater loss of cells from baseline in the CFTR-/- mice than in WT, suggesting increased Aspergillus-induced macrophage cell death (Fig 1D–F, p≤0.05).