Moreover, YY2 overexpression, which resulted in a higher rate of chromosome missegregation (Figure 7D; Figure S11D, Supporting Information), further increased anti‐PD‐L1 antibody treatment‐induced CTL infiltration into tumor lesions formed by MSI or MSS CRC cells (Figure 7E; Figure S11E,F, Supporting Information). This evidence concerns the gene YY2 and colorectal carcinoma.